Harukuni Tokuda Selected Research

3beta-methoxyserrat-14-en-21beta-ol

6/2010	Hybrids of 3alpha-methoxyserrat-14-en-21beta-ol (PJ-1) and 3beta-methoxyserrat-14-en-21beta-ol (PJ-2) and various anti-oxidants as cancer chemopreventive agents.
10/2004	Cancer chemopreventive activity of 3beta-methoxyserrat-14-en-21beta-ol and several serratane analogs on two-stage mouse skin carcinogenesis.

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Harukuni Tokuda Research Topics

Disease

142	Neoplasms (Cancer) 07/2020 - 01/2000
76	Carcinogenesis 03/2016 - 01/2000
12	Papilloma (Papillomatosis) 06/2012 - 06/2002
10	Experimental Melanoma 04/2015 - 01/2009
9	Inflammation (Inflammations) 04/2015 - 02/2002
5	Breast Neoplasms (Breast Cancer) 11/2013 - 03/2011
4	Leukemia 04/2014 - 09/2003
4	Skin Neoplasms (Skin Cancer) 12/2013 - 02/2003
3	Liver Neoplasms (Liver Cancer) 11/2013 - 01/2004
2	Prostatic Neoplasms (Prostate Cancer) 06/2013 - 03/2011
2	Melanoma (Melanoma, Malignant) 08/2010 - 12/2006
2	Hepatocellular Carcinoma (Hepatoma) 03/2009 - 01/2004

Drug/Important Bio-Agent (IBA)

52	Epstein-Barr virus early antigenIBA 03/2018 - 02/2002
38	anthraceneIBA 04/2015 - 02/2002
26	TriterpenesIBA 04/2014 - 03/2002
17	CarcinogensIBA 11/2014 - 02/2002
16	Peroxynitrous Acid (Peroxynitrite)IBA 12/2013 - 04/2002
14	AcidsIBA 04/2015 - 02/2002
8	Melanocyte-Stimulating Hormones (MSH)IBA 04/2015 - 06/2012
7	Carotenoids (Carotene)IBA 04/2014 - 01/2000
6	AntioxidantsIBA 06/2013 - 06/2002
5	1,1-diphenyl-2-picrylhydrazylIBA 12/2014 - 06/2002
5	Melanins (Melanin)IBA 03/2014 - 01/2009
5	Biological ProductsIBA 05/2013 - 02/2003
5	GlycosidesIBA 06/2012 - 02/2002
5	Phosphates (Orthophosphate)IBA 07/2008 - 11/2003
5	BuffersIBA 07/2008 - 11/2003
4	aplysiatoxinIBA 04/2017 - 10/2010
4	Acetates (Acetic Acid Esters)FDA Link 04/2014 - 08/2006
4	AntigensIBA 04/2014 - 02/2002
4	Pharmaceutical PreparationsIBA 06/2013 - 01/2008
4	EstersIBA 06/2012 - 03/2004
4	cucurbitaneIBA 02/2012 - 02/2002
4	CoumarinsIBA 02/2008 - 02/2002
4	lupaneIBA 09/2006 - 03/2002
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2006 - 06/2003
4	AlkaloidsIBA 01/2006 - 03/2002
4	9,10-Dimethyl-1,2-benzanthraceneIBA 02/2004 - 02/2003
3	Hydroxyl RadicalIBA 04/2017 - 08/2009
3	debromoaplysiatoxinIBA 01/2016 - 06/2012
3	Drinking WaterIBA 12/2013 - 06/2013
3	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2013 - 03/2011
3	Proteins (Proteins, Gene)FDA Link 10/2013 - 09/2003
3	Free RadicalsIBA 10/2013 - 06/2002
3	caproamideIBA 06/2013 - 02/2003
3	DiterpenesIBA 04/2011 - 09/2006
3	1,3- dihydroxy- 4,4,5,5- tetramethyl- 2- (4- carboxyphenyl)tetrahydroimidazole (NOR 1)IBA 09/2009 - 02/2005
3	Glycerol (Glycerine)FDA LinkGeneric 08/2009 - 03/2003
3	LupanesIBA 07/2009 - 03/2002
3	oleananeIBA 07/2009 - 03/2005
3	Emodin (Archin)IBA 07/2008 - 08/2002
3	XanthonesIBA 02/2008 - 03/2002
3	FlavonoidsIBA 02/2008 - 01/2004
3	PhytochemicalsIBA 01/2007 - 01/2000
2	Protein Kinase CIBA 04/2017 - 08/2013
2	Oleanolic AcidIBA 01/2017 - 01/2016
2	cycloartaneIBA 04/2014 - 06/2007
2	Betulinic AcidIBA 02/2014 - 07/2009
2	Dihydrotachysterol (AT 10)IBA 12/2013 - 02/2004
2	Sunscreening Agents (Sunscreens)IBA 12/2013 - 06/2013
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 11/2013 - 09/2003
2	QuinoxalinesIBA 11/2013 - 01/2011
2	interferon tauIBA 10/2013 - 03/2013
2	homoorientin (isoorientin)IBA 10/2013 - 03/2013
2	Monophenol Monooxygenase (Tyrosinase)IBA 10/2013 - 03/2013
2	IsoenzymesIBA 08/2013 - 10/2010
2	AcetoneIBA 06/2013 - 02/2003
2	Transcription Factors (Transcription Factor)IBA 03/2013 - 07/2003
2	astaxanthine (astaxanthin)IBA 01/2013 - 06/2012
2	BryostatinsIBA 06/2012 - 01/2012
2	Fatty Acids (Saturated Fatty Acids)IBA 06/2012 - 05/2007
2	ChalconesIBA 02/2012 - 01/2006
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 02/2012 - 01/2006
2	Protein Kinases (Protein Kinase)IBA 01/2011 - 10/2010
2	Phorbol EstersIBA 01/2011 - 03/2002
2	Amino Acids FDA Link 08/2010 - 02/2005
2	3beta-methoxyserrat-14-en-21beta-olIBA 06/2010 - 10/2004
2	SesquiterpenesIBA 02/2010 - 06/2003
2	CurcuminIBA 09/2009 - 01/2004
2	coumarinIBA 09/2009 - 10/2004
2	umbellipreninIBA 09/2009 - 02/2008
2	prenylIBA 02/2008 - 10/2004
2	Terpenes (Terpenoids)IBA 02/2008 - 01/2000
2	NaphthoquinonesIBA 12/2007 - 11/2003
2	SolutionsIBA 08/2006 - 07/2006
2	DiarylheptanoidsIBA 05/2006 - 10/2002
2	monascinIBA 10/2005 - 02/2005
2	QuassinsIBA 09/2004 - 11/2002
2	alpha-toxicarolIBA 06/2004 - 01/2004
2	deguelinIBA 06/2004 - 01/2004
2	nobiletinIBA 01/2004 - 01/2004
2	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 11/2003 - 02/2003
2	glycerolglycolipidsIBA 03/2003 - 12/2002
2	TeaIBA 02/2003 - 04/2002
1	IsoflavonesIBA 07/2020

Therapy/Procedure

15	Chemoprevention 03/2016 - 01/2000
7	Oral Administration 01/2013 - 02/2003
4	Therapeutics 07/2020 - 12/2006
3	Topical Administration 02/2013 - 02/2003
2	Traditional Medicine (Folk Remedies) 03/2018 - 06/2002